Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Role of Hippocampus in Memory01:19

Role of Hippocampus in Memory

2.1K
The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
2.1K
Working Memory01:24

Working Memory

1.3K
Working memory refers to a combination of components, including short-term memory and attention, that allow an individual to hold information temporarily as we perform cognitive tasks. It is an essential cognitive function that enables the execution of complex tasks such as problem-solving, comprehension, and reasoning. Unlike short-term memory, which simply involves the storage of information for a brief period, working memory involves the active manipulation and processing of this...
1.3K
Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

1.5K
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
1.5K
Encoding01:19

Encoding

1.0K
Information enters the brain through encoding, which is the input of information into the memory system. Once sensory information is received from the environment, the brain labels or codes it. The information is then organized with similar information and connected to existing concepts. Encoding occurs through automatic processing and effortful processing.
Automatic processing involves the encoding of details like time, space, frequency, and the meaning of words, usually done without conscious...
1.0K
Storage01:23

Storage

495
A schema is a mental framework that helps individuals organize and interpret information. Schemata, formed from previous experiences, influence how we process new information: how we encode it, the inferences we make, and how we retrieve it. For instance, a schema for what a typical classroom looks like might include desks, a teacher's desk, a whiteboard, and students in such an environment. This expectation helps us quickly understand and navigate new classrooms without needing to analyze...
495
Olfaction01:25

Olfaction

50.0K
The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
50.0K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Divergent transcriptomic pathways underlie sex-biased cognitive rescue by developmental GSK3B inhibition in a mouse model of 22q11.2 deletion syndrome.

Translational psychiatry·2026
Same author

Impaired spatial coding and neuronal hyperactivity in the medial entorhinal cortex of aged APP knock-in mice.

Cell reports·2026
Same author

Male Sapap3 knockout mice show threat bias under conflict during platform-mediated avoidance task: effects of extinction with response prevention and implications for obsessive compulsive disorder.

Translational psychiatry·2026
Same author

The representational geometry of emotional states in basolateral amygdala.

Nature neuroscience·2026
Same author

Stretchable Microelectrode Arrays with Microneedles for Reliable Electrophysiological Recording of Human Heart and Brain Organoids.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

A mathematical theory for understanding when abstract representations emerge in neural networks.

ArXiv·2026
Same journal

Daily briefing: 'Cyborg' cockroaches breathe underwater with printed suit.

Nature·2026
Same journal

China boosts prestigious grants for young scientists - will it ease competition?

Nature·2026
Same journal

Incoming US science academy chief vows to 'double down' on research.

Nature·2026
Same journal

Author Correction: Synthesis of enantioenriched atropisomers by biocatalytic deracemization.

Nature·2026
Same journal

Electrodeposited self-assembled molecules for perovskite photovoltaics.

Nature·2026
Same journal

Neutrino's nursery found: the 'Shadow Blaster'.

Nature·2026
関連記事をすべて見る

関連する実験動画

Updated: Apr 11, 2026

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function
06:17

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

Published on: January 26, 2024

2.8K

Hippocampal-prefrontal inputは,ワーキングメモリの空間的なエンコーディングをサポートしています.

Timothy Spellman1, Mattia Rigotti2, Susanne E Ahmari3

  • 1Department of Physiology and Cellular Biophysics, Columbia University, 630 West 168th Street, New York, New York 10032, USA.

Nature
|June 9, 2015
PubMed
まとめ
この要約は機械生成です。

海馬と前頭前皮質の間の直接的な接続は,マウスの空間情報のエンコーディングに不可欠です. この経路は,メモリタスク中に空間的シグナルを更新するために不可欠です.

さらに関連する動画

An Appetitive Spatial Working Memory Task for Mice in a Semi-Automated 8-Arm Radial Maze, Reducing Fearful Memory Association in the Maze
14:24

An Appetitive Spatial Working Memory Task for Mice in a Semi-Automated 8-Arm Radial Maze, Reducing Fearful Memory Association in the Maze

Published on: July 29, 2025

1.9K
A Video Demonstration of Preserved Piloting by Scent Tracking but Impaired Dead Reckoning After Fimbria-Fornix Lesions in the Rat
08:37

A Video Demonstration of Preserved Piloting by Scent Tracking but Impaired Dead Reckoning After Fimbria-Fornix Lesions in the Rat

Published on: April 24, 2009

12.4K

関連する実験動画

Last Updated: Apr 11, 2026

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function
06:17

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

Published on: January 26, 2024

2.8K
An Appetitive Spatial Working Memory Task for Mice in a Semi-Automated 8-Arm Radial Maze, Reducing Fearful Memory Association in the Maze
14:24

An Appetitive Spatial Working Memory Task for Mice in a Semi-Automated 8-Arm Radial Maze, Reducing Fearful Memory Association in the Maze

Published on: July 29, 2025

1.9K
A Video Demonstration of Preserved Piloting by Scent Tracking but Impaired Dead Reckoning After Fimbria-Fornix Lesions in the Rat
08:37

A Video Demonstration of Preserved Piloting by Scent Tracking but Impaired Dead Reckoning After Fimbria-Fornix Lesions in the Rat

Published on: April 24, 2009

12.4K

科学分野:

  • 神経科学は神経科学である.
  • コグニティブ・サイエンス コグニティブ・サイエンス
  • システム神経科学 システム神経科学

背景:

  • 空間的作業記憶は,空間的シグナルを数秒間にわたってキャッシュすることを含む.
  • 前頭前皮質と海馬は,空間的作業記憶のための重要な脳領域です.
  • 海馬と前頭前部の相互作用の正確な解剖学的経路とタイミングは不明である.

研究 の 目的:

  • 空間的作業記憶における海馬と前頭前部の直接的な接続の役割を調査する.
  • 記憶のエンコーディング,メンテナンス,および検索中に海馬と前頭前野の相互作用の時間的ダイナミクスを決定する.

主な方法:

  • ネズミの空間的な作業記憶のタスクを利用した.
  • 前頭前皮質におけるニューロン活動の記録.
  • 直接の海馬前頭前頭部アフェレンツが記憶のパフォーマンスと神経表現に与える影響を調査した.

主要な成果:

  • hippocampal-prefrontal afferentsは空間的なシグナルをコードするのに不可欠ですが,メンテナンスやリクエストには必要ありません.
  • 空間的なシグナルを表す前頭前部のユニットの活動は,暗号化段階のヒポカンプスの入力にのみ依存しています.
  • ヒポキャンパスと前頭前皮質の間のガンマ周波数の同期が,成功するキューエンコーディングを媒介する.

結論:

  • 直接の海馬前頭前線経路は,作業記憶中の空間情報のリアルタイム更新に重要な役割を果たします.
  • 暗号化段階における海馬からの入力が,空間的シグネルの前頭前線表現の確立に不可欠である.