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Updated: Apr 11, 2026

Isolation of Soluble and Insoluble PrP Oligomers in the Normal Human Brain
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Published on: October 3, 2012

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人間のプリオンタンパク質の自然発生の変種は,プリオン病を完全に予防します

Emmanuel A Asante1, Michelle Smidak1, Andrew Grimshaw1

  • 1MRC Prion Unit, Department of Neurodegenerative Disease, UCL Institute of Neurology, London WC1N 3BG, UK.

Nature
|June 11, 2015
PubMed
まとめ

G127Vプリオンタンパク質 (PrP) 変種は, kuru と Creutzfeldt-Jakob 病 (CJD) などのプリオン疾患に対して完全な耐性を提供しています. この変異種はまた,他のプリオン菌株の伝播を強力に抑制します.

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