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Updated: Apr 9, 2026

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
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感染症. 感染症. デザイナーのタンパク質は,強力なHIV防御を産生する

Jon Cohen

    Science (New York, N.Y.)
    |June 20, 2015
    PubMed
    まとめ

    No abstract available in PubMed .

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    Protein synthesis is indispensable for viral replication, as viruses lack the cellular machinery required for this process and must hijack the host's translational apparatus. In response, host cells deploy a critical innate immune defense involving interferons, specialized cytokines that play a central role in inhibiting viral propagation.Upon viral detection, infected cells release interferons that bind to receptors on adjacent uninfected cells, activating the JAK-STAT signaling pathway and...
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