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Updated: Apr 9, 2026

Comparing the Affinity of GTPase-binding Proteins using Competition Assays
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シグナル翻訳. ヘテロトリメリックGタンパク質における核酸交換の構造的基礎

Ron O Dror1, Thomas J Mildorf2, Daniel Hilger3

  • 1D. E. Shaw Research, New York, NY 10036, USA. ron.dror@deshawresearch.com david.shaw@deshawresearch.com.

Science (New York, N.Y.)
|June 20, 2015
PubMed
まとめ

Gタンパク質結合受容体 (GPCRs) は,Gタンパク質からニュクレオチドを放出することによって信号を発する. 原子シミュレーションにより,GPCRsはGタンパク質の内部構造変化を促進することを明らかにしました.

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