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Updated: Apr 9, 2026

Real-time Analysis of Transcription Factor Binding, Transcription, Translation, and Turnover to Display Global Events During Cellular Activation
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Real-time Analysis of Transcription Factor Binding, Transcription, Translation, and Turnover to Display Global Events During Cellular Activation

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アクティビティ依存トランスクリプションへのショートカット

Nikhil Sharma1, Harrison W Gabel1, Michael E Greenberg1

  • 1Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.

Cell
|June 20, 2015
PubMed
まとめ

研究者らは,トポイソメラーゼIIB (酵素) が予期せぬ形でプロモーターDNAを切断することを発見しました. この切断作用は,神経細胞活動によって活性化された遺伝子の転写を促進します.

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