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幹細胞の増殖と癌におけるDNAセンサーAIM2の重要な役割

Si Ming Man1, Qifan Zhu2, Liqin Zhu3

  • 1Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

Cell
|June 23, 2015
PubMed
まとめ

生まれながらの免疫センサーAIM2は,腸の幹細胞の増殖を制御することによって,大腸がんから保護します. AIM2の喪失は,腸内微生物群の変化と組み合わせて,結腸腫瘍の発症を増加させます.

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