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Updated: Apr 8, 2026

Assays for the Degradation of Misfolded Proteins in Cells
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整体膜タンパク質 PMP2222の適合安定性と病原性誤折り

Jonathan P Schlebach, Malathi Narayan, Catherine Alford1

  • 1#Flow Cytometry Core, Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee 37232, United States.

Journal of the American Chemical Society
|June 24, 2015
PubMed
まとめ

周辺ミエリンタンパク質22 (PMP22) のタンパク質折り畳み安定性の変化は,その細胞の密輸に直接影響を及ぼし,シャルコ・マリー・トゥース病 (CMT) の新しい治療標的を提供します. この研究は,タンパク質エネルギーと疾患の重症性を関連付けています.

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