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Updated: Apr 8, 2026

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RNAバイオケミストリー. 人間のeIF4A DEAD-boxヘリケーゼにおける因子依存のプロセシビティ

Cuauhtémoc García-García1, Kirsten L Frieda2, Kateryna Feoktistova3

  • 1Department of Biology, Stanford University, Stanford, CA 94305, USA.

Science (New York, N.Y.)
|June 27, 2015
PubMed
まとめ

ユカリオットの翻訳開始因子4A (eIF4A) は,eIF4GとeIF4Bの助けを借りて,非進行性ではなく,プロセス性ヘリケーゼとして作用します. これは,翻訳中のmRNAスキャンのための段階的なメカニズムを明らかにします.

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