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Updated: Apr 7, 2026

Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods
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デング熱のサブゲノムRNAはTRIM25と結合し,流行病学的適性のためにインターフェロン発現を抑制します

Gayathri Manokaran1, Esteban Finol2, Chunling Wang3

  • 1Program in Emerging Infectious Diseases, Duke-National University of Singapore Graduate Medical School, Singapore. Defence Medical and Environmental Research Institute, DSO National Laboratories, Singapore. Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

Science (New York, N.Y.)
|July 4, 2015
PubMed
まとめ

新しいデング熱ウイルス (DENV) 株 (PR-2B DENV-2) は,より多くのサブゲノムフラビウイルスRNA (sfRNA) を生成することによって,その流行の可能性を高めました. このsfRNAは宿主の免疫反応を回避し,ウイルスの適性を高めます.

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