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生命の起源に関する概念としてのリボフィルム
John A Baross1, William F Martin2
1School of Oceanography and Astrobiology Program, University of Washington, Seattle, WA 98195, USA.
Cell
|July 4, 2015
まとめ
最も初期のアーカイアはメタンを生成し,生命の起源に関する水熱風口仮説を支持した. これは,RNAが生命の初期に自己複製機ではなく,基礎的なプラットフォームとして機能したことを示唆しています.
科学分野:
- 天体生物学 アストロバイオロジー
- バイオケミストリー バイオケミストリー
- 地質学 地質学 地質学
背景:
- 系統遺伝学的データは,初期のアーカイアがメタノゲンであったことを示唆しています.
- 熱水噴出孔は,アビオゲネシスの主要な仮説である.
- 生命の起源におけるRNAの役割は議論されている.
研究 の 目的:
- 系統遺伝子のデータを熱水噴出孔の理論と統合する.
- 生命の初期におけるRNAの役割に関する新しいモデルを提案する.
- 熱力学的に導かれたアビオゲネシスの仮説を支持するために.
主な方法:
- 古代生物の系統遺伝分析.
- 初期の地球条件の熱力学モデリング.
- 生化学経路の再構築.
主要な成果:
- 最近の系統遺伝学データは,最初のアーカイアがメタン産物であったことを示している.
- この発見は,熱水噴出口から生じた生命の分野を超えた証拠を活性化します.
- "リボフィルム"という概念が提案されています.
結論:
- 生命は,水熱噴出口で熱力学的に誘導された出来事によって発生した可能性が高い.
- RNAの生命の起源の役割は,ゆっくりと変化するプラットフォームとしてよりよく説明されるかもしれません.
- これは,純粋に自発的な自己複製体としてのRNAの概念に挑戦しています.
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