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CREBの共同活性化剤CRTC2は,SREBP1を調節することによって,肝臓の脂質代謝を制御する

Jinbo Han1, Erwei Li1, Liqun Chen1

  • 1MOE Key Laboratory of Bioinformatics, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.

Nature
|July 7, 2015
PubMed
まとめ

CREB調節型転写共活性化剤2 (CRTC2) は,ステロール調節要素結合タンパク質1 (SREBP1) の輸送を調節することによって,脂質代謝に影響を与えます. この発見は,非アルコール性脂肪肝疾患とインスリン抵抗性の治療に関する新しい洞察を提供します.

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