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Solid-phase Synthesis of [4.4] Spirocyclic Oximes
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不飽和オキシムから2,3-ジヒドロピリジンへのアクセスは,Rh (((III)) -Catalyzed C-H アクティベーションによる迅速なアクセスです

Fedor Romanov-Michailidis1, Kassandra F Sedillo1, Jamie M Neely1

  • 1Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States.

Journal of the American Chemical Society
|July 9, 2015
PubMed
まとめ

この研究は,不飽和のオキシムピヴァラートとオレフィンからダイヒドロピリジンを合成するために,ロジウム (III) 複合体を用いた新しい触媒法を導入しています. これらの化合物は,価値ある医薬品の構成要素であるパイペリジンに容易に水素化することができます.

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