関連する実験動画

Updated: Apr 7, 2026

Author Spotlight: Exploring the Relationship Between Lipotoxicity and HFpEF
03:42

Author Spotlight: Exploring the Relationship Between Lipotoxicity and HFpEF

Published on: March 29, 2024

2.2K

D374Y-PCSK9高コレステロールミニピッグにおける持続的な流動障害を誘発すると,アテロゲネシスを加速し,薄いキャップ線維腫の発達を促進する

Ryan M Pedrigi1, Christian Bo Poulsen1, Vikram V Mehta1

  • 1From Department of Bioengineering, Imperial College London, United Kingdom (R.M.P., V.V.M., A.L.P., R.K.); Institute of Clinical Medicine, Aarhus University Hospital, Denmark (C.B.P., N.R.H., M.M.B., N.P.A., A.K.G., J.F.B., E.F.); Department of Cardiology, Aarhus University Hospital, Denmark (C.B.P., N.R.H., M.M.B., N.P.A., A.K.G., J.F.B., H.E.B., E.F.); NIHR Cardiovascular Biomedical Research Unit, Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom (I.D.K., W.A.S.B., G.D.'A., A.M., C.D.M., R.d.S.); Graduate Medical School, Duke-National University of Singapore, Singapore (E.P.); National Heart Centre, NHRIS, Singapore (N.F.); National Heart and Lung Institute, Imperial College London, United Kingdom (C.D.M., R.d.S.); and Institute of Cardiovascular Medicine and Science, Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom (C.D.M., R.d.S.).

Circulation
|July 17, 2015
PubMed
まとめ

血流の乱れ,特に低圧または多方向切断は,進行冠動脈硬化プラークの発生を誘発する. 細いキャップのフィブロアテロマという 危険なプラークの形成の鍵となるものです

キーワード:
動脈硬化症生体物理学エンドセリウム血液動力学プラーク,動脈硬化切断ストレストモグラフィー,光学コヒーレンス

さらに関連する動画

Implantation of a Carotid Cuff for Triggering Shear-stress Induced Atherosclerosis in Mice07:51

Implantation of a Carotid Cuff for Triggering Shear-stress Induced Atherosclerosis in Mice

Published on: January 13, 2012

21.3K
Quantification of Atherosclerosis in Mice06:59

Quantification of Atherosclerosis in Mice

Published on: June 12, 2019

41.1K

関連する概念動画

Atherosclerosis I: Introduction01:30

Atherosclerosis I: Introduction

Atherosclerosis is a progressive disorder characterized by the buildup of plaques on the arterial inner wall, causing them to narrow and harden over time. These plaques comprise lipids, calcium, blood components, carbohydrates, and fibrous tissue. The process primarily affects the intima of large and medium-sized arteries, reducing blood flow in any artery.Etiology and risk factorsThe cause of atherosclerosis is multifactorial, involving a complex interplay among endothelial injury, lipid...
2.0K
Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
637
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
994
Inflammation01:38

Inflammation

Overview
64.6K