関連する実験動画

Updated: Apr 6, 2026

Single Particle Cryo-Electron Microscopy: From Sample to Structure
11:52

Single Particle Cryo-Electron Microscopy: From Sample to Structure

Published on: May 29, 2021

10.0K

ナノ粒子のイメージング 電子顕微鏡による溶液中の個々のナノ結晶の3D構造

Jungwon Park1, Hans Elmlund2, Peter Ercius3

  • 1Department of Chemistry, University of California, Berkeley, CA 94720, USA. Department of Applied Physics, Harvard University, Cambridge, MA 02138, USA. School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA.

Science (New York, N.Y.)
|July 18, 2015
PubMed
まとめ

研究者は,高度な電子顕微鏡を用いて溶液中の個々のナノ粒子の3D構造を決定する新しい方法を開発しました. この突破は,異質なナノ粒子集団におけるナノスケールの欠陥分析を可能にします.

さらに関連する動画

Single Particle Electron Microscopy Reconstruction of the Exosome Complex Using the Random Conical Tilt Method12:10

Single Particle Electron Microscopy Reconstruction of the Exosome Complex Using the Random Conical Tilt Method

Published on: March 28, 2011

24.0K
Microcrystal Electron Diffraction of Small Molecules09:48

Microcrystal Electron Diffraction of Small Molecules

Published on: March 15, 2021

7.3K

関連する概念動画

Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
3.0K
Cryo-electron Microscopy01:28

Cryo-electron Microscopy

Conventional electron microscopy (EM) involves dehydration, fixation, and staining of biological samples, which distorts the native state of biological molecules and results in several artifacts. Also, the high-energy electron beam damages the sample and makes it difficult to obtain high-resolution images. These issues can be addressed using cryo-EM, which uses frozen samples and gentler electron beams. The technique was developed by Jacques Dubochet, Joachim Frank, and Richard Henderson, for...
4.6K