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関連する概念動画

Mechanism of Ciliary Motion01:05

Mechanism of Ciliary Motion

5.8K
The ciliary structures were first seen in 1647 by Antonie Leeuwenhoek while observing the protozoans. In lower organisms, these appendages are responsible for cell movement, while in higher organisms, these appendages help in the movement of the extracellular fluids within the body cavities.
The cilia are made up of microtubules in a 9+2 arrangement, with nine microtubule doublet ring bundles, surrounding a pair of central singlet microtubule bundles. The doublet microtubule bundles are...
5.8K
Mechanism of Ciliary Motion01:05

Mechanism of Ciliary Motion

2.7K
2.7K
Aromatic Hydrocarbon Cations: Structural Overview01:18

Aromatic Hydrocarbon Cations: Structural Overview

4.3K
Cycloheptatriene is a neutral monocyclic unsaturated hydrocarbon that consists of an odd number of carbon atoms and an intervening sp3 carbon in the ring. The three double bonds in the ring correspond to 6 π electrons, which is a Huckel number, and therefore satisfies the criteria of 4n + 2 π electrons. However, the intervening sp3 carbon disrupts the continuous overlap of p orbitals. As a result, cycloheptatriene is not aromatic.
Removing one hydrogen from the intervening CH2 group...
4.3K
Tension Response at Adherens Junctions01:26

Tension Response at Adherens Junctions

4.3K
The adherens junctions that anchor cells together are multi-protein complexes that dynamically adapt to mechanical stimuli such as tensile forces and shear stress. Mechanosensory proteins in these junctions can sense such mechanical stimuli and undergo a shift in their conformation, resulting in an altered function — a process called mechanotransduction.
α-Catenin as a Mechanosensory Protein
The α-catenin of adherens junctions is an allosteric protein with three VH (vinculin...
4.3K
Catenins01:23

Catenins

3.3K
Catenins are characterized by multiple binding domains and dynamic structures that allow them to function as linker proteins in cell junction complexes. All catenins, except α-catenin, contain a characteristic protein sequence called the armadillo repeat and are therefore also called armadillo proteins.
Catenins in Cell Junctions
Catenins bind to cell adhesion molecules such as cadherins and link them to different cytoskeletal proteins depending on the type of cell junction. At the...
3.3K
Chair Conformation of Cyclohexane02:02

Chair Conformation of Cyclohexane

21.6K
The chair conformation is the most stable form of cyclohexane due to the absence of angle and torsional strain. The absence of angle strain is a result of cyclohexane’s bond angle being very close to the ideal tetrahedral bond angle of 109.5° in its chair conformer. Similarly, the torsional strain is also absent owing to the perfectly staggered arrangement of bonds.
The hydrogen atoms linked to carbons are arranged in two different axial and equatorial orientations to achieve this...
21.6K

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関連する実験動画

Updated: Apr 6, 2026

High-Contrast and Fast Photorheological Switching of a Twist-Bend Nematic Liquid Crystal
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High-Contrast and Fast Photorheological Switching of a Twist-Bend Nematic Liquid Crystal

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マルチバレンットの段階的な動き [2]

Zheng Meng1,2, Ying Han1, Li-Na Wang3

  • 1†Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.

Journal of the American Chemical Society
|July 18, 2015
PubMed
まとめ
この要約は機械生成です。

研究者は新しい三重連鎖カテネンを開発しました この分子機械は 酸塩変化によって引き起こされる 段階的な動きを示し 生物分子機械の仕組みに 洞察を与えます

さらに関連する動画

Synthesis of Cyclic Polymers and Characterization of Their Diffusive Motion in the Melt State at the Single Molecule Level
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Synthesis of Cyclic Polymers and Characterization of Their Diffusive Motion in the Melt State at the Single Molecule Level

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Motility of Single Molecules and Clusters of Bi-Directional Kinesin-5 Cin8 Purified from S. cerevisiae Cells
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Motility of Single Molecules and Clusters of Bi-Directional Kinesin-5 Cin8 Purified from S. cerevisiae Cells

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関連する実験動画

Last Updated: Apr 6, 2026

High-Contrast and Fast Photorheological Switching of a Twist-Bend Nematic Liquid Crystal
06:24

High-Contrast and Fast Photorheological Switching of a Twist-Bend Nematic Liquid Crystal

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Synthesis of Cyclic Polymers and Characterization of Their Diffusive Motion in the Melt State at the Single Molecule Level
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Motility of Single Molecules and Clusters of Bi-Directional Kinesin-5 Cin8 Purified from S. cerevisiae Cells
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Motility of Single Molecules and Clusters of Bi-Directional Kinesin-5 Cin8 Purified from S. cerevisiae Cells

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科学分野:

  • 超分子化学
  • 化学工学
  • 生物分子工学

背景:

  • 生物分子の機械は 形状の変化を含む多段階のプロセスを経て動作します
  • これらの複雑な動きを理解することは 人工分子機械の設計に不可欠です

研究 の 目的:

  • 新型三重鎖 [2](3) カテナンを報告する.
  • このカテネンの 段階的な酸塩触発運動を 調べるため
  • 分子機構の構造変化と動態を明らかにする.

主な方法:

  • 新しい三重相互接続 [2](3) 宿主-ゲストシステムの合成.
  • 酸塩定位を用いて 段階的な動きを誘発し定量化します
  • 安定した形状状態の直接的識別と定量化
  • ダイナミクスを特徴付けるための解離定数 (pKa) の値の決定.

主要な成果:

  • 合成された [2] (((3) カテナンは,段階的な酸塩触発運動を示した.
  • 4つの安定した構成状態が特定され,定量化され,多段階のプロセスを確認しました.
  • pKa値は環境酸性によるダイナミクスを定量化して決定した.
  • カテネンのトポロジーは,特定のゲストサイトのためにホストリングの選択的運動を誘導します.

結論:

  • この研究は,複雑な分子機械の段階的な動きを成功裏に実証し,特徴づけました.
  • 複雑な生物学的分子機械のメカニズムに 洞察を与えてくれます
  • この研究は,高度な機械化学的性質を持つ人工分子機械を設計するための基盤を提供します.