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Updated: Apr 6, 2026

Integrate Imaging Flow Cytometry and Transcriptomic Profiling to Evaluate Altered Endocytic CD1d Trafficking
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BACE1の活性と阻害を調節する

Christopher R Ellis1, Jana Shen1

  • 1Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland 21201, United States.

Journal of the American Chemical Society
|July 18, 2015
PubMed
まとめ

ベータ分泌酵素1 (BACE1) の活動は,形状の変化によってpHによって調節される. このpHに依存するメカニズムを理解することは アルツハイマー病の治療を最適化するための鍵です

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