関連する実験動画

Updated: Apr 6, 2026

A Microwave-Assisted Direct Heteroarylation of Ketones Using Transition Metal Catalysis
07:06

A Microwave-Assisted Direct Heteroarylation of Ketones Using Transition Metal Catalysis

Published on: February 16, 2020

8.7K

ニトロアシストブレンステッド酸触媒: 挑戦的な触媒酸化への応用

Marian Dryzhakov, Malik Hellal, Eléna Wolf

    Journal of the American Chemical Society
    |July 22, 2015
    PubMed
    まとめ

    窒素化合物は,B ((C6F5) 3·H2Oを用いた三次アルコールのアジデーションのための最初の触媒周回を可能にします. この突破は,窒素化合物が活性ブレンステッド酸触媒として作用する水素結合積分を形成することを明らかにします.

    さらに関連する動画

    Preparation of Contiguous Bisaziridines for Regioselective Ring-Opening Reactions04:38

    Preparation of Contiguous Bisaziridines for Regioselective Ring-Opening Reactions

    Published on: July 28, 2022

    3.6K
    A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones07:30

    A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

    Published on: January 21, 2020

    8.8K

    関連する概念動画

    Electrophilic Aromatic Substitution: Nitration of Benzene01:20

    Electrophilic Aromatic Substitution: Nitration of Benzene

    The nitration of benzene is an example of an electrophilic aromatic substitution reaction. It involves the formation of a very powerful electrophile, the nitronium ion, which is linear in shape. The reaction occurs through the interaction of two strong acids, sulfuric and nitric acid.
    9.8K
    1° Amines to Diazonium or Aryldiazonium Salts: Diazotization with NaNO2 Mechanism01:37

    1° Amines to Diazonium or Aryldiazonium Salts: Diazotization with NaNO2 Mechanism

    Nitrous acid is a relatively weak and unstable acid prepared in situ by the reaction of sodium nitrite and cold, dilute hydrochloric acid. In an acidic solution, the nitrous acid undergoes protonation when it loses water to form a nitrosonium ion—an electrophile. Nitrous acid reacts with primary amines to give diazonium salts. The reaction is called diazotization of primary amines.
    5.3K
    Preparation of 1° Amines: Azide Synthesis01:22

    Preparation of 1° Amines: Azide Synthesis

    Direct alkylation of ammonia produces polyalkylated amines, along with a quaternary ammonium salt. To exclusively prepare primary amines, the azide synthesis method can be used.
    Azide ions act as good nucleophiles and react with unhindered alkyl halides to form alkyl azides. Alkyl azides do not participate in further nucleophilic substitution reactions, thereby eliminating the chances of polyalkylated products. Alkyl azides are reduced by hydride-based reducing agents, like lithium aluminum...
    4.8K
    α-Bromination of Carboxylic Acids: Hell–Volhard–Zelinski Reaction01:15

    α-Bromination of Carboxylic Acids: Hell–Volhard–Zelinski Reaction

    The method to achieve α-brominated carboxylic acids using a mixture of phosphorus tribromide and bromine is known as the Hell–Volhard–Zelinski reaction. The reaction is catalyzed by phosphorus tribromide, which can be used directly or produced in situ from red phosphorus and bromine. The mechanism comprises PBr3 catalyzed conversion of acid to acid bromide and hydrogen bromide. The acid bromide enolizes to its enol form in the presence of HBr. The nucleophilic enol attacks the...
    4.0K
    Preparation of Amines: Reductive Amination of Aldehydes and Ketones01:38

    Preparation of Amines: Reductive Amination of Aldehydes and Ketones

    Carbonyl compounds and primary amines undergo reductive amination first to produce imines, followed by secondary amines in the same reaction mixture, using selective reducing agents like sodium cyanoborohydride or sodium triacetoxyborohydride. Reductive amination produces different degrees of substitution of amines depending on the starting amine substrate.
    4.2K
    Preparation of Amines: Reduction of Oximes and Nitro Compounds01:29

    Preparation of Amines: Reduction of Oximes and Nitro Compounds

    Oximes can be reduced to primary amines using catalytic hydrogenation, hydride reduction, or sodium metal reduction. The reduction of aliphatic and aromatic nitro compounds to primary amines takes place by either catalytic hydrogenation or by using active metals like Fe, Zn, and Sn in the presence of an acid.
    Though catalytic hydrogenation can reduce nitrobenzenes, the reduction is nonselective in the presence of other functional groups. For instance, if nitrobenzene contains an aldehyde group,...
    4.9K