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Updated: Apr 6, 2026

Ex utero Electroporation and Whole Hemisphere Explants: A Simple Experimental Method for Studies of Early Cortical Development
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Published on: April 3, 2013

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ニューロ開発 大人の皮質の可塑性は,出生後の早期の臨界期に依存する

Stuart D Greenhill1, Konrad Juczewski2, Annelies M de Haan1

  • 1School of Biosciences, Cardiff University, Cardiff, CF23 3AX, UK.

Science (New York, N.Y.)
|July 25, 2015
PubMed
まとめ

マウスの早期発達の間にDISC1のシグナル伝達を妨害すると,シナプス可塑性が低下し,成人期に長期の増強とうつ病に影響する. これはDISC1変異に関連した認知障害と精神症状を説明する可能性がある.

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