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メタボリズム S-ニトロシレーションは,肥満に関連した炎症とエンドプラズマ網膜機能障害を関連付けています

Ling Yang1, Ediz S Calay1, Jason Fan1

  • 1Department of Genetics and Complex Diseases and Sabri Ülker Center, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.

Science (New York, N.Y.)
|August 1, 2015
PubMed
まとめ

肥満における炎症は,誘導性酸化窒素合成酵素 (iNOS) 活動を通じて,内プラズマ網膜 (ER) のストレス反応を損なう. これはERホメオスタシスとタンパク質機能を損なっており,肥満に関連する合併症に寄与します.

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