レジオネール病
Burke A Cunha1, Almudena Burillo2, Emilio Bouza3
1Infectious Disease Division, Winthrop-University Hospital, Mineola, NY, USA; School of Medicine, State University of New York, Stony Brook, NY, USA.
Lancet (London, England)
|August 2, 2015
まとめ
レジオネラ菌は レジオネール病を 引き起こします 肺炎は 汚染された水源と よく関連しています この潜在的に致命的な感染症の管理には 意識の向上と診断の改善が不可欠です
科学分野:
- 微生物学
- 感染症
- 公衆衛生
背景:
- 1977年に特定されたレジオネラ菌は,コミュニティで発症する肺炎の重要な原因であり,病院で発症する肺炎の稀な原因である.
- このバクテリアは 水中の環境や 建物の水システムに生息し, レギオネア病を 引き起こします これは重度の多系統感染症で 主に脆弱な個人に 影響を及ぼします
- レジオネロシスの増加は,その生態系と病原性の理解の進歩とともに,疾患の認識と報告の強化を反映している可能性があります.
研究 の 目的:
- レジオネール病の流行病学,病原性,臨床的症状に関する現在の理解をレビューする.
- 非特異的な症状と現在の診断テストの限界による診断の課題を強調する.
- 疫病発生制御のための疾病通知システムの重要性と効果的な抗生物質治療の可用性を強調する.
主な方法:
- レジオネラとレジオネール病の文献レビュー
- 流行病学的傾向と診断上の課題の分析
- 病原性,臨床表現,管理に関する現在の知識の統合.
主要な成果:
- レジオネラ菌は肺炎の一般的な原因で,罹患率が増加しています.
- 年齢や免疫抑制などの要因により,感受性の高い集団はリスクが高い.
- 効果的な抗生物質の治療にも関わらず 診断の敏感性は依然として課題です
結論:
- レジオネール病は非特異的な症状により 高い臨床的疑念を必要とする.
- 疫病の流行を抑えるには 効果的な監視と通知システムが不可欠です
- 診断と病原性に関する継続的な研究は 患者の改善のために不可欠です
関連する概念動画
01:14Atypical Pneumonia
47
Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease...
47
01:30Pneumonia I: Introduction
1.3K
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
1.3K
01:29Pneumonia II: Pathophysiology
4.2K
The pathophysiology of pneumonia involves the following steps:
4.2K
01:28Diphtheria
93
Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
93
01:30Bacterial Phylum Spirochaetes
1.2K
Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased...
1.2K
01:25Cholera
72
Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...
72