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Updated: Apr 6, 2026

Retroviral Scanning: Mapping MLV Integration Sites to Define Cell-specific Regulatory Regions
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RAG は リンパ球 ゲノム に 広く 脅威 を 及ぼす

Grace Teng1, Yaakov Maman1, Wolfgang Resch2

  • 1Department of Immunobiology, Yale University School of Medicine, 300 Cedar Street, Box 208011, New Haven, CT 06520-8011, USA.

Cell
|August 4, 2015
PubMed
まとめ

RAG1-RAG2複合体はリンパ球内の活性遺伝子領域を標的にし,ゲノムに近くの特定のDNA配列を減らすように促します. この進化的適応は 危険なDNA破裂や染色体転位を防ぐことができます

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