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Updated: Apr 6, 2026

Delivery of Proteins, Peptides or Cell-impermeable Small Molecules into Live Cells by Incubation with the Endosomolytic Reagent dfTAT
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Delivery of Proteins, Peptides or Cell-impermeable Small Molecules into Live Cells by Incubation with the Endosomolytic Reagent dfTAT

Published on: September 2, 2015

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タウリンは,酵素による細胞内分子自己組み立てのための小型のDペプチドの細胞吸収を促進する

Jie Zhou1, Xuewen Du1, Jie Li1

  • 1Department of Chemistry, Brandeis University, 415 South Street, Waltham, Massachusetts 02453, United States.

Journal of the American Chemical Society
|August 4, 2015
PubMed
まとめ

タウリン結合は,哺乳類の細胞におけるD-ペプチドの細胞吸収を10倍以上強化する. この戦略により細胞内自己組織化が可能になり,蓄積が改善され,Dペプチドの新たな生物医学的な応用が可能になる.

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