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Updated: Apr 5, 2026

Purification of Hsp104, a Protein Disaggregase
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Purification of Hsp104, a Protein Disaggregase

Published on: September 30, 2011

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重要なHSP70コチャペロン複合体はメタゾーンタンパク質の分解を解除する

Nadinath B Nillegoda1, Janine Kirstein2, Anna Szlachcic1

  • 1Center for Molecular Biology of the University of Heidelberg (ZMBH), German Cancer Research Center (DKFZ), DKFZ-ZMBH Alliance, 69120 Heidelberg, Germany.

Nature
|August 7, 2015
PubMed
まとめ

メタゾーン細胞は,新しいJタンパク質複合体を使用して,HSP70システムを介してタンパク質集積物を効率的に分解します. この発見は,ヒトとネマトードにおける細胞タンパク質の品質管理のための新しいメカニズムを明らかにしています.

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