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Updated: Apr 5, 2026

Visualizing the Conformational Dynamics of Membrane Receptors Using Single-Molecule FRET
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クラスCのGタンパク質結合受容体の構成動態

Reza Vafabakhsh1, Joshua Levitz1, Ehud Y Isacoff1,2,3

  • 1Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, USA.

Nature
|August 11, 2015
PubMed
まとめ

この研究では,メタボトロピックグルタミン酸受容体 (mGluR) の活性化には,リガンド結合,リガンド結合ドメイン (LBD) 閉塞,およびダイマーインターフェースシフトが含まれています. 異なるmGluRは独特のダイナミクスを示し,神経機能に影響を与えます.

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