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Isolation and Kv Channel Recordings in Murine Atrial and Ventricular Cardiomyocytes
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低血量症による心房動の分子基礎

Arash Pezhouman1, Neha Singh1, Zhen Song1

  • 1UCLA Cardiovascular Research Laboratory, Departments of Medicine (Cardiology) and Physiology, David Geffen School of Medicine at UCLA, Los Angeles, CA.

Circulation
|August 14, 2015
PubMed
まとめ

低血量症 (低カリウム) は,特にドフェチリドにより,CaMKIIと遅いNa電流を活性化することによって,心律異常を促します. Na-Kポンプの阻害は このフィードバックループの鍵です

キーワード:
抗不律剤心臓発作長いQTシンドロームカリウム信号変換

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