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Updated: Apr 5, 2026

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ヒトのγ-セクレターゼの原子構造

Xiao-Chen Bai1, Chuangye Yan2, Guanghui Yang2

  • 1MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

Nature
|August 18, 2015
PubMed
まとめ

アルツハイマー病において重要なヒトのガンマ分泌酵素 (γ-分泌酵素) の原子構造は,プレシニリン1 (PS1) ホットスポットに影響する変異を明らかにする. これは酵素の機能と病気のメカニズムを理解するための分子基盤を提供します.

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