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Updated: Apr 5, 2026

Measuring Interactions of Globular and Filamentous Proteins by Nuclear Magnetic Resonance Spectroscopy NMR and Microscale Thermophoresis MST
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Measuring Interactions of Globular and Filamentous Proteins by Nuclear Magnetic Resonance Spectroscopy NMR and Microscale Thermophoresis MST

Published on: November 2, 2018

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タンパク質結合部位を特定するためのパラマグネティック・リガンド・タグ付け

Ulrika Brath1, Shashikala I Swamy1, Alberte X Veiga1

  • 1Department of Chemistry and Molecular Biology and the Swedish NMR Centre, University of Gothenburg , SE-412 96 Gothenburg, Sweden.

Journal of the American Chemical Society
|August 21, 2015
PubMed
まとめ

研究者は,低親和性タンパク質-リガンド結合部位を特定するための新しいパラマグネティック・リガンドタグ方法を開発した. この技術はNMRの偽接触シフトを用いて相互作用をマッピングし,医薬品開発に役立ちます.

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