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Updated: Apr 5, 2026

Preparation of Nucleosome Core Particles Complexed with DNA Repair Factors for Cryo-Electron Microscopy Structural Determination
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Published on: August 17, 2022

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メタゾーンNup62•Nup58•Nup54ヌクレオポリン複合体の結晶構造

Hema Chug1, Sergei Trakhanov1, Bastian B Hülsmann1

  • 1Department of Cellular Logistics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.

Science (New York, N.Y.)
|August 22, 2015
PubMed
まとめ

構造分析により,Nup62複合体は核孔複合体 (NPC) の内部に長方形の障壁を形成していることが明らかになった. この構造は,以前のモデルとは異なり,NPCチャネル全体の輸送選択性を規制するメカニズムを示唆しています.

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