移植後の受容体自然キラー細胞のアロ認識と適応性アロ免疫への影響

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Updated: Apr 4, 2026

Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade
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Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade

Published on: March 14, 2011

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Jason Ali1, Ines Harper1, Eleanor Bolton1

  • 1Department of Surgery, University of Cambridge, Cambridge, UK.

Lancet (London, England)
|August 28, 2015
PubMed
まとめ

心臓移植におけるドナーのCD4T細胞による移植対宿主認識は,アロレスポンスを増幅し,自己免疫性を高めます. 宿主NK細胞によるこれらの細胞の急速な殺戮は,慢性的な拒絶と自己抗体発達の予防に不可欠です.

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