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骨髄増殖性腫瘍におけるJAK/ STAT経路の活性化に対するメソトレクサートの効果

Sally Thomas1, Katherine Fisher2, John Snowden3

  • 1Sheffield Cancer Research Centre, University of Sheffield, Sheffield, UK.

Lancet (London, England)
|August 28, 2015
PubMed
まとめ

メソトレクサートは,骨髄増殖性腫瘍の重要な要因であるJAK/ STAT経路を阻害する. この薬は骨髄繊維症を含むこれらの血液がんの費用対効果の高い治療法として有望です.

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