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Updated: Apr 4, 2026

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細胞内タンパク質相互作用を標的としたα/βペプチド折りたたみ

James W Checco, Erinna F Lee1,2, Marco Evangelista1

  • 1The Walter and Eliza Hall Institute of Medical Research , Parkville, Victoria 3052, Australia.

Journal of the American Chemical Society
|August 29, 2015
PubMed
まとめ

アルファアミノ酸とベータアミノ酸を組み合わせた改造ペプチドは,安定性と細胞浸透性を高めています. これらの新しいアルファ/ベータペプチドは,アポトーシスに関わるタンパク質の相互作用を効果的に阻害し,治療の可能性を向上させます.

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