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Updated: Apr 4, 2026

Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes
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Published on: November 1, 2012

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Staphylococcus aureus Cas9の結晶構造について

Hiroshi Nishimasu1, Le Cong2, Winston X Yan3

  • 1Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan; JST, PRESTO, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan.

Cell
|August 29, 2015
PubMed
まとめ

研究者らは,Staphylococcus aureus Cas9 (SaCas9) の結晶構造を解明し,多様なDNA標的を認識するメカニズムを明らかにした. この構造的な洞察は,先進的なCRISPR-Cas9ゲノム編集ツールの開発を可能にします.

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