腎臓がん
Umberto Capitanio1, Francesco Montorsi2
1Department of Urology, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Lancet (London, England)
|August 31, 2015
まとめ
腎臓細胞癌 (RCC) の診断と治療は急速に進化し,生存率が向上しています. 進歩には積極的な監視,最小侵襲的手術,標的治療が含まれていますが,進行した疾患では課題が残っています.
科学分野:
- 腫瘍学
- 泌尿器科
背景:
- 腎臓細胞癌 (RCC) の発生率は上昇していますが,生存率は著しく改善しています.
- 小規模で不活性なRCCの偶発的な診断は一般的です.
- 局所的に進行した疾患や転移性疾患は依然として大きな課題です
研究 の 目的:
- 腎臓細胞がんの診断と治療における最近の進歩をレビューする.
- 局所性および進行性RCCの治療戦略の進化を強調する.
- RCCケアにおける現在の不確実性と将来の研究方向性を特定する.
主な方法:
- 最近の臨床試験とガイドラインのレビュー
- RCCの診断と治療方法の動向の分析
- 手術技術,監視,全身治療に関するデータの統合
主要な成果:
- 活発な監視と腎臓を節約する外科技術 (例えば,ロボットによる手術) の採用を拡大する.
- 小さな腫瘍の 熱処理のような 侵襲的処置の普及です
- 手術と標的型生物学的薬剤を組み合わせた統合された戦略により,高度なRCCの治療結果を改善します.
結論:
- RCCの管理における顕著な進歩は,特に初期段階での生存率の向上につながりました.
- 手術による脱毛と標的型全身治療を組み合わせた統合されたアプローチは,進行したRCCの治療を改善します.
- 進行中の研究は,残っている課題に対処し,腎臓細胞癌の患者のアウトカムをさらに改善するために不可欠です.
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