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Updated: Apr 4, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
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ディオキサビサイクロオクタン環系を含む真菌ポリケチドの効率的な生物合成

Xu-Ming Mao1, Zha-Jun Zhan2, Matthew N Grayson

  • 1College of Life Sciences, Zhejiang University , Hangzhou 310058, China.

Journal of the American Chemical Society
|September 5, 2015
PubMed
まとめ

アデノシン三リン酸合成酵素を阻害する菌性ポリケチドであるオーロヴェルチンは,簡潔な経路で合成される. 4つの酵素がポリエンの前駆体を複合的なダイオキサビサイクロ[3.2.1]オクタン基板に変換し,効率的な天然製品生物合成を示しています.

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