関連する実験動画

Updated: Apr 4, 2026

Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology
07:04

Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology

Published on: May 2, 2025

1.3K

メラノマ細胞の内在的なPD-1受容体の機能が腫瘍の成長を促す

Sonja Kleffel1, Christian Posch2, Steven R Barthel1

  • 1Harvard Skin Disease Research Center, Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

Cell
|September 12, 2015
PubMed
まとめ

メラノーマ細胞のプログラム細胞死1 (PD-1) は,免疫細胞がなくても腫瘍の成長を促します. この内在的なPD-1経路を阻害することで メラノーマの進行を遅らせ,新たな治療目標を示唆する.

キーワード:
メラノーマPD-1 についてPD-L1 についてS6 リボソームタンパク質抗体について封鎖する免疫チェックポイントmTORシグナリングp-S6 についてプログラム細胞死-1治療法

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