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関連する概念動画

Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

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Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
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Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

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Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
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Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

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Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
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Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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Heart Failure I: Introduction01:27

Heart Failure I: Introduction

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Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
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Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

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The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
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このページは機械翻訳されています。他のページは英語で表示される場合があります。View in English
  1. ホーム
  3. 研究分野
  5. 生物医学と臨床科学
  7. 心血管医学と血液学
  9. 心臓病 (心血管疾患を含む)
  11. 大規模医療センターでの追跡中の現代の成人先天性心疾患患者の生存見通しと死亡状況

大規模医療センターでの追跡中の現代の成人先天性心疾患患者の生存見通しと死亡状況

Gerhard-Paul Diller1, Aleksander Kempny2, Rafael Alonso-Gonzalez1

  • 1From Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension, Royal Brompton Hospital, London, United Kingdom (G.-P.D., A.K., R.A.-G., L.S., A.U., W.L., S.B.-N., S.J.W., K.D., M.A.G.); NIHR Cardiovascular Biomedical Research Unit, Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, United Kingdom (G.-P.D., A.K., R.A.-G., L.S., A.U., W.L., S.B.-N., S.J.W., K.D., M.A.G.); National Heart and Lung Institute, Imperial College School of Medicine, London, United Kingdom (G.-P.D., A.K., R.A.-G., L.S., A.U., W.L., S.B.-N., S.J.W., K.D., M.A.G.); and Division of Adult Congenital and Valvular Heart Disease, Department of Cardiology and Angiology, University Hospital Muenster, Germany (G.-P.D.).

Circulation
|September 16, 2015

関連する実験動画

Implantation of Total Artificial Heart in Congenital Heart Disease
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Implantation of Total Artificial Heart in Congenital Heart Disease

Published on: July 18, 2014

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Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model
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Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model

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A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death
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A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death

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PubMed で要約を見る

まとめ
この要約は機械生成です。

成人の先天性心疾患 (ACHD) の患者は,特に複雑な状態の患者は,より高い死亡率に直面します. 心臓疾患以外の死因は 癌のように ACHDの生存者の年齢とともに顕著になります

科学分野:

  • 心臓病科
  • 大人の先天性心臓病 (ACHD)
  • 公衆衛生

背景:

  • 大人の先天性心疾患 (ACHD) の患者は,長期にわたる有意な罹病率と生存率の低下を経験します.
  • ACHDセンターの専門的なフォローアップは,ますます重要であると認識されています.
  • この研究は,大規模なACHDコホートにおける生存と死亡の原因を評価しています.

研究 の 目的:

  • 成人の先天性心疾患患者の生存の可能性を評価する.
  • この集団における死因を特定し分析する.
  • 死亡率を一般人と比較する

主な方法:

  • 1991年から2013年の間に6969人の成人患者を追跡した.
  • 公式の死亡証明書から死因の確認
  • 生存率と年齢と性別を合わせた一般集団のデータとの比較

主要な成果:

  • 9. 1年の追跡期間中,死亡者数は524人でした.
  • 主な死因:慢性心不全 (42%),肺炎 (10%),突然の心臓死 (7%),がん (6%).
  • アイゼンメンガー症候群,複合性ACHD,Fontan生理学の患者は生存率が著しく低下した.
キーワード:
心臓障害,先天性心不全死亡率心臓発作による突然死

関連する実験動画

Implantation of Total Artificial Heart in Congenital Heart Disease
07:27

Implantation of Total Artificial Heart in Congenital Heart Disease

Published on: July 18, 2014

25.4K
Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model
04:55

Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model

Published on: May 26, 2023

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A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death
07:08

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death

Published on: June 6, 2025

780

結論:

  • ACHD患者は,特に高齢化とともに,一般の人々と比較して死亡率が高くなります.
  • 複合性 ACHD,フォントンの生理学,そしてアイゼンメンガー症候群は,最も高い死亡率と関連しています.
  • この研究は,現代のACHD患者の非心臓死因のスペクトルを強調しています.
生存率