科学 的 な 発見 から 治療: 銀河 の 中 で の 明るい 星
R Sanders Williams1, Samad Lotia2, Alisha K Holloway1
1Gladstone Institutes, San Francisco, CA 94158, USA; University of California, San Francisco, San Francisco, CA 94143, USA.
Cell
|September 26, 2015
まとめ
公共のデータベースのデータマイニングと ネットワーク分析により 科学的発見と 医学的な治療の関連が明らかになります これらの方法は,生命科学の研究に対する公衆の支持を高め,治療法を追求する意思決定を改善することができます.
科学分野:
- 生物医学情報学
- 翻訳医学
- 科学的発見分析
背景:
- 基礎的研究と臨床的発見の関係を理解することは 医学進歩にとって極めて重要です
- 科学的影響を追跡するための既存の方法は,しばしば定量的な厳格性が欠けている.
- 公共のデータベースは,科学的な取り組みに関する相互接続されたデータの豊富な情報源です.
研究 の 目的:
- 科学的発見と医療治療の関係をマッピングするためにデータマイニングとネットワーク分析を使用する方法を提案し概説する.
- 医療研究と公共の関与の促進におけるこれらの計算手法の可能性を強調する.
- 定量分析が生命科学の戦略的決定にどのように役立つかを示します.
主な方法:
- 公共の科学データベースから関連する情報を抽出するためにデータマイニング技術を使用します.
- ネットワーク分析を用いて,様々な研究成果の関連性を視覚化し,定量化します.
- 基本的発見と治療の成果を結びつけるパターンを特定するための計算的フレームワークの開発
主要な成果:
- 提案されたアプローチは,科学的発見と主要な医療進歩 (治療法) の間の関係を体系的に特定し,定量化することができます.
- ネットワーク分析は科学的な状況の 視覚的,定量的な表現を提供します.
- データマイニングは 基礎科学から臨床応用までの 未知の経路を明らかにします
結論:
- データマイニングとネットワーク分析は 医学研究の進展を理解するための強力なツールです
- これらの計算手法により,生命科学の研究への公的・政府的な支援が強化され,その効果が実証されます.
- これらのアプローチのさらなる開発は,治療法を探し出す際に重要な意思決定を助けることができます.
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