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Updated: Apr 2, 2026

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HIV-1 Nefは,SERINC5をビリオンの組み込みから排除することによって感染を促進します

Annachiara Rosa1, Ajit Chande1, Serena Ziglio1

  • 1University of Trento, Centre for Integrative Biology, 38123 Trento, Italy.

Nature
|September 30, 2015
PubMed
まとめ

ヒト免疫不全ウイルス1型 (HIV-1) Nefタンパク質は,HIV-1の感染性を抑制する宿主タンパク質であるSERINC5の抗ウイルス活性に対抗する. Nefは,SERINC5を新しいウイルス粒子に組み込み,それによってウイルスの拡散を増加させます.

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