Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Neuronal Communication01:28

Neuronal Communication

5.1K
Neurons, the fundamental units of the brain and nervous system, communicate through complex electrochemical signals that underpin all cognitive and bodily functions. This communication is primarily facilitated by a process involving the generation and propagation of an action potential along the axon of the neuron. When the internal electrical charge of a neuron surpasses a certain threshold, an action potential is triggered. This rapid change in voltage travels swiftly along the axon to the...
5.1K
Neurons as Communicators of the Brain01:22

Neurons as Communicators of the Brain

4.9K
Neurons, the fundamental units of the brain and nervous system, function as the primary transmitters of information throughout the body. Their ability to communicate through electrical and chemical signals is vital for every bodily function, from regulating the heartbeat to processing complex thoughts. Each neuron has three main components: the cell body (soma), dendrites, and an axon, each specialized to facilitate swift and efficient neural communication.
Cell Body
The cell body, also known...
4.9K
Electrical Synapses01:28

Electrical Synapses

11.8K
Electrical synapses found in all nervous systems play important and unique roles. In these synapses, the presynaptic and postsynaptic membranes are very close together (3.5 nm) and are actually physically connected by channel proteins forming gap junctions.
Gap junctions allow the current to pass directly from one cell to the next. In contrast, in the chemical synapse, the neurotransmitters carry the information through the synaptic cleft from one neuron to the next. They consist of two...
11.8K
The Role of Ion Channels in Neuronal Computation01:19

The Role of Ion Channels in Neuronal Computation

4.2K
A postsynaptic neuron usually receives numerous impulses from several other presynaptic neurons. The axon hillock of the postsynaptic neuron integrates all these signals and determines the likelihood of firing an action potential.
Sometimes a single EPSP is strong enough to induce an action potential in the postsynaptic neuron. However, multiple presynaptic inputs must often create EPSPs around the same time for the postsynaptic neuron to be sufficiently depolarized to fire an action potential....
4.2K
Neural Circuits01:25

Neural Circuits

3.2K
Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
3.2K
Organization of the Brain01:30

Organization of the Brain

3.7K
The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
3.7K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Amyloid precursor protein ortholog Appl acts with Vnd during mushroom body axon growth in Drosophila.

Genetics·2026
Same author

Building brains, shaping behaviors: How developmental approaches illuminate the analysis of circuits and behavior.

Current opinion in neurobiology·2026
Same author

Variants in the proteasome regulator PSMF1 cause a phenotypic spectrum from parkinsonism to perinatal lethality.

Nature communications·2026
Same author

Adherens junctions balance stability and motility: from cell morphogenesis to neural tissue patterning.

Biological chemistry·2026
Same author

Selective adhesion preserves eye patterning as axonal retinotopy in the Drosophila brain.

Current biology : CB·2026
Same author

Heterozygous pathogenic variants in the splicing factor SF1 lead to a large spectrum of neurodevelopmental disorders.

American journal of human genetics·2025
Same journal

Co-option of lysosomal machinery shapes the evolution of the intracellular photosymbiosis supporting coral reefs.

Cell·2026
Same journal

LEF1 and niche factors determine T cell stemness across chronic diseases.

Cell·2026
Same journal

Recurrent patterns of TOP1-mediated neuronal genomic damage shared by major neurodegenerative disorders.

Cell·2026
Same journal

Four-dimensional molecular mapping from a spatial snapshot reveals the dynamics of hair follicle organogenesis.

Cell·2026
Same journal

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data.

Cell·2026
Same journal

Systematic discovery of pathogen effector functions across human pathogens and pathways.

Cell·2026
関連記事をすべて見る

関連する実験動画

Updated: Apr 1, 2026

Microdissection of Mouse Brain into Functionally and Anatomically Different Regions
08:06

Microdissection of Mouse Brain into Functionally and Anatomically Different Regions

Published on: February 15, 2021

58.4K

複雑 な 脳 に 繋がる シンプル な 規則

Bassem A Hassan1, P Robin Hiesinger2

  • 1Center for the Biology of Disease, VIB, 3000 Leuven, Belgium; Center for Human Genetics, University of Leuven School of Medicine, 3000 Leuven, Belgium.

Cell
|October 10, 2015
PubMed
まとめ
この要約は機械生成です。

この研究は 脳の配線に関する 伝統的な分子コード理論に 挑戦しています 複雑なコードではなく,単純な発達アルゴリズムとパターン形成規則が,神経回路の特異性を保証することを提案しています.

さらに関連する動画

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks
11:18

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks

Published on: March 2, 2015

11.0K
Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits
10:32

Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits

Published on: April 15, 2015

9.0K

関連する実験動画

Last Updated: Apr 1, 2026

Microdissection of Mouse Brain into Functionally and Anatomically Different Regions
08:06

Microdissection of Mouse Brain into Functionally and Anatomically Different Regions

Published on: February 15, 2021

58.4K
Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks
11:18

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks

Published on: March 2, 2015

11.0K
Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits
10:32

Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits

Published on: April 15, 2015

9.0K

科学分野:

  • 神経科学
  • 発達生物学
  • コンピュータ生物学

背景:

  • 分子コードは伝統的に脳の配線における特定のニューロン標的の選択に不可欠と考えられています
  • 神経回路の複雑さから 純粋な分子コードは 曖昧な生成を想定するのは困難です

研究 の 目的:

  • 神経科学における分子コードの概念を再検討する
  • 発達アルゴリズムに基づく神経回路の特異性についての代替説明を探求する.
  • 脳の配線を理解するための パターンベースの枠組みを提案します

主な方法:

  • 神経発達における分子メカニズムに関する既存の概念の再評価.
  • 分子やメカニズムがパターン形成のルールをどのように実装できるか分析する.
  • 神経回路の構築のためのパターンベースのフレームワークの理論的描写.

主要な成果:

  • 以前は"コード"の一部と考えられていた分子やメカニズムは,代わりに単純なパターン形成ルールとして機能する.
  • これらのパターン形成規則は,ニューラル回路の配線特異性を確保するのに十分です.
  • 神経発達のコードベースの理解からパターンベースの理解への移行が提案されています.

結論:

  • 神経線路の分子コードという伝統的な概念は 複雑な回路では不十分かもしれません
  • パターン形成を用いた開発アルゴリズムは,配線特異性を確保するための実行可能な代替案を提供します.
  • このパターンに基づく枠組みは 脳の配線のメカニズムに 新たな洞察を与えてくれます