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An Optogenetic Method to Control and Analyze Gene Expression Patterns in Cell-to-cell Interactions
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相対パルスタイミングの調節による結合遺伝子調節

Yihan Lin1,2, Chang Ho Sohn3, Chiraj K Dalal1,2

  • 1Howard Hughes Medical Institute, California Institute of Technology, Pasadena, California 91125, USA.

Nature
|October 16, 2015
PubMed
まとめ

細胞は遺伝子発現を制御するために 転写因子パルスのタイミングを利用します アクティベーター Msn2とリプレッサー Mig1はパルスタイミングを調整することで標的遺伝子を調節し,新しい時間ベースの遺伝子調節メカニズムを明らかにします

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