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Updated: Mar 31, 2026

Utilizing Murine Inducible Telomerase Alleles in the Studies of Tissue Degeneration/Regeneration and Cancer
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Published on: April 13, 2015

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高リスクの神経芽細胞腫におけるゲノム再編によるテロメラーゼ活性化

Martin Peifer1,2, Falk Hertwig2,3, Frederik Roels2,3

  • 1Department of Translational Genomics, Center of Integrated Oncology Cologne-Bonn, Medical Faculty, University of Cologne, 50931 Cologne, Germany.

Nature
|October 16, 2015
PubMed
まとめ

テロメラーゼ逆転写酵素遺伝子 (TERT) の近くのゲノム再編成は,高リスクの神経芽細胞腫でその発現を活性化させ,悪い結果をもたらします. テロメラーゼの活性化はこのような 侵襲的な小児がんの重要な要因です

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