関連する実験動画

Updated: Mar 31, 2026

Bead Aggregation Assays for the Characterization of Putative Cell Adhesion Molecules
08:15

Bead Aggregation Assays for the Characterization of Putative Cell Adhesion Molecules

Published on: October 17, 2014

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プロトカデリン領域相互作用によるニューロンの自己認識の分子論理

Rotem Rubinstein1, Chan Aye Thu2, Kerry Marie Goodman2

  • 1Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA; Department of Systems Biology, Columbia University, New York, NY 10032, USA.

Cell
|October 20, 2015
PubMed
まとめ

クラスタ化されたプロトカデリンは,特定の細胞の認識を通じて神経の自己回避を媒介する. この研究は,プロトカデリンのドメインがダイマーを形成し,神経発達の過程でサイズに依存した自己認識を可能にするために相互作用することを明らかにしています.

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Structure of Cadherins

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Immunoglobulin-like cell adhesion molecules or Ig-CAMs are a versatile group of cell surface glycoproteins belonging to the immunoglobulin protein superfamily. Ig-CAMs possess the characteristic immunoglobulin protein domains and other domains such as the fibronectin type III domain. The Ig domains are glycosylated to varying degrees in different Ig-CAMs.
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