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Updated: Mar 31, 2026

Detection of Viral RNA by Fluorescence in situ Hybridization FISH
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Published on: May 5, 2012

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HIV-1 NefはAP-1:Arf1ポリゴンを安定させ,クラトリンのコートをハイジャックする

Qing-Tao Shen1, Xuefeng Ren1, Rui Zhang2

  • 1Department of Molecular and Cell Biology and California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA 94720, USA.

Science (New York, N.Y.)
|October 24, 2015
PubMed
まとめ

ヒト免疫不全ウイルス (HIV) のネフタンパク質とArf1はAP-1クラスリン層を再構成する. Cryo-EM構造は,これらのタンパク質がウイルスの複製と膜の移動に不可欠な六角組成を形成する方法を明らかにします.

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A High-throughput Cre-Lox Activated Viral Membrane Fusion Assay to Identify Inhibitors of HIV-1 Viral Membrane Fusion

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