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システインの生物結合のための有機金属パラジウム反応剤

Ekaterina V Vinogradova1, Chi Zhang1, Alexander M Spokoyny1

  • 1Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

Nature
|October 30, 2015
PubMed
まとめ

研究者は効率的なシステイン生物結合のためのパラジアム (II) 複合体を開発した. この方法により,穏やかな条件下で堅固なタンパク質の改変が可能になり,様々な用途に適した安定したアリル生物結合物が生成されます.

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