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Updated: Mar 31, 2026

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine
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化学療法による抗腫瘍免疫には,ホルミルペプチド受容体1が必要です

Erika Vacchelli1, Yuting Ma2, Elisa E Baracco3

  • 1Gustave Roussy Cancer Campus, Villejuif, France. INSERM, U1138, Paris, France. Équipe 11 Labellisée par la Ligue Nationale Contre le Cancer, Centre de Recherche des Cordeliers, Paris, France. Université Paris Descartes, Sorbonne Paris Cité, Paris, France. Université Pierre et Marie Curie, Paris, France.

Science (New York, N.Y.)
|October 31, 2015
PubMed
まとめ

甲状腺ペプチド受容体1 (FPR1) 機能喪失アレルは,死滅する癌細胞との dendritic 細胞の相互作用を阻害し,抗腫瘍免疫を低下させることで,化学療法の有効性を損なう. これは,効果的ながん治療への対応において,FPR1の重要な役割を強調しています.

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