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Updated: Mar 30, 2026

Induction of Intestinal Inflammation by Adoptive Transfer of CBir1 TCR Transgenic CD4+ T Cells to Immunodeficient Mice
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CTLA-4ブロックによる抗がん免疫療法は,腸内微生物群に依存する

Marie Vétizou1, Jonathan M Pitt1, Romain Daillère1

  • 1Institut de Cancérologie Gustave Roussy Cancer Campus (GRCC), 114 rue Edouard Vaillant, 94805 Villejuif, France. INSERM U1015, GRCC, Villejuif, France. University of Paris Sud XI, Kremlin-Bicêtre, France.

Science (New York, N.Y.)
|November 7, 2015
PubMed
まとめ

CTLA-4 (細胞毒性Tリンパ球関連タンパク質4) に対する抗体を用いたがん免疫療法は,特定の腸内細菌,特にバクテロイド種に依存しています.

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