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Updated: Mar 30, 2026

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

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アザ-オキシアリルカチオン介質のディオロマティブインドールサイクル添加反応:ピロロインドリンへのモジュールアクセス

Arjun Acharya1, Devendar Anumandla1, Christopher S Jeffrey1

  • 1Department of Chemistry, University of Nevada , Reno, Nevada 89557-0216, United States.

Journal of the American Chemical Society
|November 13, 2015
PubMed
まとめ

新種の dearomative aza-(3 + 2) サイクロアディション反応により,インドールから機能化されたピロロインドリンの効率的な合成が可能になります. この方法は,天然産物フィソスティグミンを合成するために使用されました.

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