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Updated: Mar 30, 2026

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes
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トライオセフォスファートイソメラーゼによる触媒におけるループクランプサイドチェーンの役割

Xiang Zhai1, Tina L Amyes1, John P Richard1

  • 1Department of Chemistry, University at Buffalo, SUNY , Buffalo, New York 14260-3000, United States.

Journal of the American Chemical Society
|November 17, 2015
PubMed
まとめ

トリオフォスファートイソメラーゼ (TIM) の変異は酵素触媒に影響する. ほとんどの変異は基質結合と移行状態を同様に変化させ,一部の変異は触媒部位の反応性に影響する.

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