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Updated: Mar 29, 2026

Author Spotlight: Achieving High-Purity In Vitro Differentiation of Th17 Cells Using Cytokine Concentration Modulation
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Author Spotlight: Achieving High-Purity In Vitro Differentiation of Th17 Cells Using Cytokine Concentration Modulation

Published on: October 25, 2024

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CD5L/AIM 脂質生物合成を調節し,Th17細胞の病原性を抑制する

Chao Wang1, Nir Yosef2, Jellert Gaublomme3

  • 1Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.

Cell
|November 27, 2015
PubMed
まとめ

CD5L/ AIMタンパク質はTヘルパー17 (Th17) 細胞の病原性を調節し,自己免疫を予防する. CD5Lの損失は,非病原性Th17細胞を病原性細胞に変換し,脂質代謝を変化させます.

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