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Updated: Apr 30, 2026

Budding Yeast Protein Extraction and Purification for the Study of Function, Interactions, and Post-translational Modifications
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S. cerevisiaeは,哺乳類のBiPに序列と機能で同類である必須タンパク質をコードする

K Normington1, K Kohno, Y Kozutsumi

  • 1Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas 75235.

Cell
|June 30, 1989
PubMed
まとめ

哺乳類のBiPタンパク質は,分泌タンパク質の折り畳みを促進する. 細胞成長に不可欠な酵母BiPは,KAR2と同一であり,BiPの欠乏がエンドプラズマ網膜における広範なタンパク質の誤折れを引き起こすことを示唆しています.

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